The overwhelming majority of the DNA of eukaryotic organisms does not encode proteins. Although scientists do not know the function of this
seemingly "junk" DNA, they have learned how to exploit it. One example is the use of DNA microsatellites. Microsatellites are blocks
of a few (<5) nucleotides that are repeated multiple times. Errors in DNA replication lead to variability in the number of times that
the block is repeated. The polymorphism that results can serve as the basis for genetic markers.
Publication
- A practical approach to microsatellite genotyping with special reference to livestock population genetics. Manual [pdf, 353 kb].