Nuclear Medicine and Diagnostic Imaging (NMDI)
Co-ordinated Research Projects
Nuclear Cardiology:
CRP Number: E1.30.34
Year of Commencement: 2007 |
CRP Number: E1.30.32 Myocardial perfusion imaging is an emerging technique to help triage patients presenting to the emergency room with chest pain and who present with a normal or non-diagnostic electrocardiogram. The method has been shown to demonstrate a high cost saving and decrease length of stay in hospital. In essence, a normal study allows the sage discharge of the patient from the emergency department. The purpose of our study is to extrapolate these data to the developing world and to assess the ability of this technique to predict the 30 day cardiac event rate. Year of Commencement: 2007 |
CRP Number: E1.30.31 To examine the prevalence of ischemia by SPECT perfusion imaging performed during symptom limited treadmill or bicycle exercise and compare it to an age and sex-matched control group with no diabetes but with multiple coronary risk factors Year of Commencement: 2006 |
CRP Number: E1.30.38 To examine the prevalence of ischemia by SPECT perfusion imaging performed during symptom limited treadmill or bicycle exercise and compare it to an age and sex-matched control group with no diabetes but with multiple coronary risk factors Year of Commencement: 2010 |
Nuclear Oncology:
CRP Number: E1. 50.20 To develop prognostic algorithms to improve the treatment and outcome of patients with aggressive non-Hodgkin’s Lymphoma in developing countries. Year of Commencement: 2006 |
CRP Number: E1.30.33 The objective of this CRP is to evaluate the clinical safety and efficacy of 177Lu-EDTMP for bone pain palliation in metastatic prostate cancer in a Phase I and Phase II clinical trial. Effective cancer management requires standardizing and coordinating treatment protocols and by making available economically affordable therapies. Our approach will utilize available capacities in to improve access to cost effective treatment by developing appropriate infrastructure, radio pharmacy and clinical institutions to promote effective use of targeted radionuclide therapy Member States. Prostate cancer is currently one of the most common malignancies worldwide. About 50-70% of patients present with locally advanced stage and about 15-30% have bone metastases at the time of diagnosis. In advanced stage of the disease, cancer spread to the skeleton occurs in a majority of patients, with skeletal metastases being predominantly osteoblastic in nature. Treatment with bone seeking beta-emitting radiopharmaceuticals has been shown to reduce pain for a prolonged period and to improve quality of life with no serious side effects. For several reasons 177Lu-EDTMP has a very good potential for use as a therapeutic agent. Year of Commencement: 2007 |
Infection Imaging:
CRP Number: E1.30.35 To define the incremental value of combined functional and anatomical imaging by SPECT/CT in the assessment of bone infection over scintigraphy alone. Year of Commencement: 2008 |