Nuclear Medicine
Publications produced by the Section
Chloroquine-resistant Plasmodium falciparum infections among UK travellers returning with malaria after chloroquine prophylaxis. Journal of Antimicrobial Chemotherapy, 2007; 59:1197-9
Prevalent PFMDRI N86Y Mutant Plasmodium falciparum in Madagascar despite Absence f PFCRT Mutant Strains The American Society of Tropical Medicine and Hygiene, 76(6), 2007; pp. 1079-1083
Field-based evidence for the linkage of pfcrt and pfdhfr drug-resistant malaria genotypes and clinical profiles of severe malaria in Niger. Microbes and Infection, Volume 9, Issue 5, April 2007, pp.599-604
Sulfadoxine-Pyrimethamine Efficacy and Selection of Plasmodium Falciparum DHFR Mutations in Burkina Faso before its Introduction as Intermittent Preventive Treatment for Pregnant Women Am. J. Trop. Med., 76(4), 2007; pp 608-613
Predominance of a single genotype of Mycobacterium tuberculosis in regions of Southern Africa Int J. Tuberc Lung Dis. 2007; 11:311-8
Trypanosoma cruzi: Substractive hybridization as a molecular strategy to generate new targets to distinguish groups and hybrids. Experimental parasitology,Vol 117, Issue 2, 2007; pp 178-187
Spoliogype Signatures in the Mycobacterium tuberculosis Complex J Clin Microbiol. 45:237-240.
Predominance of a single genotype of Mycobacterium tuberculosis in regions of Southern Africa. Int.J.Tuberc.Lung Dis. 11:311-318
Comparative analysis of MR imaging, Ictal SPECT and EEG in temporal lobe epilepsy: a prospective IAEA multi-center study Eur J Nucl Med Mol Imaging. 2007;34; pp-pp, [Epub ahead of print]
Radiosynovectomy using yttrium-90, phosphorus-32 and rhenium-188 colloids in rheumatoid arthritis Eur J Nucl Med Mol Imaging. 2007;34:S136 (Suppl
Management of Haemarthrosis applying Radiosynovectomy in Haemophilia patients with emphasis on developing countries Eur J Nucl Med Mol Imaging. 2007;34:P439 (Suppl)
Blood and urine biokinetics of rhenium-188 tin and phosphorus-32 colloids in radiosynovectomy Eur J Nucl Med Mol Imaging. 2007;34:P476 (Suppl)
Statistical analysis of multi-centre study for the coordinate research project of IAEA: Role of radionuclide techniques in the diagnosis of early dementia J Nucl Med. 2007;48:S254 (Suppl 2).
Role of Tc-99m-ECD-brain SPECT in evaluation of patients with dementia and mild cognitive impairment: Baseline and follow-up study. Joint Molecular Imaging Conference 2007, Abstract Book: 363
Comparison of scintigraphic algorithms for the diagnosis of pulmonary embolism: Multi-centre study for IAEA coordinated research project. Eur J Nucl Med Mol Imaging 2007; 34:S239 (Suppl 2)
Randomized Comparison of Amodiaquine plus Sulfadoxine-Pyrimethamine, Artemether-Lumefantrine, and Dihydroartemisinin-Piperaquine for the Treatment of Uncomplicated Plasmodium falciparum Malaria in Burkina Faso CID 2007; 45 pp 1453-1461
Phylogenetic Analysis of the NS5 Gene of Dengue Viruses Isolated in Ecuador Virus Research 4 dec 2007 (Epub ahead of print)
Criteria for Palliation of Bone Metastases — Clinical Applications IAEA TECDOC Series No. 1549, IAEA, Vienna (2007).
Training Programmes for Developing Countries Journal of inherited metabolic disease, 2007, 30:596-599
New Interventions for Malaria: Mining the Human and Parasite Genomes Am. J. Trop. Med. Hyg. 77(Suppl 6),2007 pp 270-275
Bayesian coalescent inference of Hepatitis A virus populations: evolutionary rates and patterns Journal of General Virology, 2007, 88, 3039-3042
Multicenter Study of the Molecular basis of Thalassemia Intermedia in Different Ethnic Populations Hemoglobin, 31:4, 439-452
Prevalence of Plasmodium falciparum chloroquine resistant gene markers, Pfcrt-76 and Pfmdr-1 86, eight years after cessation of chloroquine use in Mwea, Kenya J Infect Developing countries 2007;1:195-201
Influence of global cerebral blood flow on SPECT-Episodic memory correlation in patients with mild cognitive impairment. Eur J Nucl Med Mol Imaging. 2007; 34:S134 (Suppl 2).
International cooperative clinical research on the use of statistical analysis for SPECT findings in the diagnosis of early dementia Eur J Nucl Med Mol Imaging. 2007; 34: S257 (Suppl 2).
Molecular genotyping in a malaria treatment trial in Uganda - unexpected high rate of new infections within two weeks after treatment. Trop. Med. Int. Health, Vol. 12, No. 2, Feb 2007, pp 219-223 (5)
Efficacy of Artesunate plus Amodiaquine, artesunate plus sulfadoxine-pyrimethamine in patients with uncomplicated Plasmodium falciparum in the Comoros Union. Acta Tropica, Volume 102; Issue 3, June 2007, Pages 176-181
Cross Sectional Study Reveals a High Percentage of Asymptomatic Plasmodium Vivax in the Amazon Rio Nergo Area, Brazil Rev. Inst. Med. Trop. S. Paulo 49(3); 159-164, May-June, 2007
High frequency of Plasmodium falciparum PfCRT K76T and PfpghN86Y in patients clearing infection after chloroquine treatment in the Sudan Acta Tropica, 2006; 97:19-25
Molecular genotyping to distinguish between recrudescents and new infections in treatment trials of Plasmodium falciparum malaria conducted in Sub-Saharan Africa: adjustment of parasitological outcomes and assessment of genotyping effectiveness Trop. Med. Int. Health, 2006;9:1350-1359
First evidence of mutant pfcrt Plasmodium falciparum in Madagascar Trans. R. Soc. Trop. Med. Hyg., 2006;100:826-830
The effects of alpha-1-acid glycoprotein on the potential clinical application of the reversal of chloroquine resistance phenomenon. Annals of Tropical Medicine and Parasitology, 2006; 100: 571-578
Evidence of recombination in quasispecies populations of an Hepatitis C Virus patient undergoing anti-viral therapy Virology Journal, 2006; 3:87
Comparison between radioisotopic and non-radioisotopic PCR-SSCP for the detection of mutations at the rpoB gene associated with Rifampicin resistance in mycobacterium tuberculosis, submitted for publication in WJNM. WJNM, 2006, 5, 241-247
Linkage disequilibrium between two distinct loci in chromosomes 5 and 7 of Plasmodium falciparum and in vivo chloroquine resistance in Southwest Nigeria Parasitol Res., Volume 100, Number 1, December 2006 , pp. 141-148(8)
Beyond the Visible: Managing Heart Disease and Cancer with Nuclear Science public information brochure, IAEA/PI/A.91/06-29901, 2006
Hb Bart’s in Cord Blood: An accurate indicator of á-Thalassemia Hemoglobin, 2006;30: 57-62
Association between mutations in pfcrt and pfmdr1 genes and in vivo amodiaquine resistance in falciparum malaria-infected children in Nigeria Am. J. Trop. Med. Hygiene, 2006;75: 155-161
Evidence of structural genomic region recombination in Hepatitis C virus Virology Journal, 2006;3:53
Confirmation of emergence of mutations associated with Atovaquone/proguanil resistance in unexposed Plasmodium falciparum isolates from Africa. Malaria Journal, 2006; 5:82
Nuclear Medicine Resources Manual Document link
Screening of Newborn for Congenital Hypothyroidism Document link
Predominance of Trypanosma rangeli infection in children from a Chagas disease endemic area in Panama. Memorias do Instituto Oswaldo Cruz, 2005, 100:729-731
Prevalence of Plasmodium falciparum mutations associated with antimalarial drug resistance during an epidemic in Kuna Yala, Panama, Central America. Journal of the American Society of Tropical Medicine and Hygiene, 2005, 73:839-841.
Evaluación de métodos moleculares para el diagnóstico y la caracterización de aislados de Leishmania obtenidos de pacientes en Panamá. Tecnomédica, 2005, 2, 1-4.
Multicenter Evaluation of Reverse Line Blot Assay to Predict Drug Resistance in Mycobacterium tuberculosis Clinical Isolates Microbiol. Methods, 2004 Jun;57(3):323-35
Analysis of genetic variability of Indian isolates of Hepatitis C virus Arch Virol. 2004 Jun;149(6):1185-92. Epub 2004 Mar 1.
Comparison of Hepatitis C viral loads in patients with or without co-infection of different genotypes Clin Diagn Lab Immunol. 2004 Mar;11(2):433-5.
Serodiagnosis of chronic and acute Chagas´Disease with Tripanosoma cruzi recombinant proteins: results of a collaborative study in Latin America countries. Journal of Clinical Microbiology 2004; 42(1): 449-52.
Analysis of genetic variability of Indian isolates of Hepatitis C virus. Arch Virol. 2004; 149 :1185-92.
Comparison of hepatitis C viral loads in patients with or without co-infection with different genotypes. Clin Diagn Lab Immunol. 2004;11: 433-5.
Evidence of intratypic recombination in natural populations of hepatitis C virus. J Gen Virol. 2004; 85 :31-7.
FRASCH A C. Differential accumulation of mutations localized in particular domains of the mucin genes expressed in the vertebrate host stage of Trypanosoma cruzi. Mol. Biochem. Parasitol. 2004; 133(1): 81-91.
The role and future of in-vitro isotopic techniques in molecular biology. World J. Nucl. Med. Submitted, 2004, Vol 3, (1),72-81.
Typing of HPV in Zimbabwean patients with invasive cancer of the uterine cercix Acta Obstet Gynecol Scand. Aug;82(8):762-6, 2003.
Polymorphism at 308 Promoter position of the tumour necrosis factor – alpha (TNF-a) gene and cervical cancer Int J Gynaecol cancer, 13(2):148-153, 2003.
A novel reverse transcriptase-polymerase chain reaction based-liquid hybridisation (RT-PCR-LH) assay for early diagnosis of dengue infection The Ceylon Medical J, 48(1):17-22, 2003.
Molecular characterization of alpha thalassemia in Pakistan.Hemoglobin 27 (3); 161-166
Evaluation of PCR-SSCP analysis for the detection of the rpoB mutations associated with resistance to rifampicin in Mycobacterium tuberculosis World Journal on Nuclear Medicine 2(1):45-51, 2003.
Molecular detection of drug resistance in microbes by isotopic techniques: the IAEA experience World J Nucl Med, Jan 2003. 2(1):52-59.
Development of internet-based study materials for teaching and training in nuclear medicine: Results of an IAEA coordinated research project IAEA, Vienna (Austria) New horizons: Nuclear energy in a changing world. Scientific forum during the 47th Regular Session of the IAEA General Conference (2003). 33 p.p. 15-16. INIS-XA--653
Efficay and toxicity of Sm-153 EDTMP in the palliative treatment of painful bone metastases World Journal of Nuclear Medicine, October (2002), v.1(1) p. 21-27
Trans-arterial Rhenium-188 Lipiodol in the treatment of inoperable hepatocellular carcinoma-An IAEA sponsored multi-centre phase 1 study World Journal of Nuclear Medicine, October (2002), v.1(1) p. 5-11
Tele-facilities for medicine, imaging, quality controls and maintenance services in the health sector for the developing countries and its present and future scope in Bangladesh Abdus Salam International Centre for Theoretical Physics, Trieste. Jan (2002) 10 p. IC--2002/2
Comparison of coutcomes of bone scan, clinical judgement and other imaging modalities in the pre-operative assessment of mandibular invasion by squamous cell carcinoma of oral cavity World Journal of Nuclear Medicine, October (2002), J, 34-005132
Diagnostic value of 99mTc-methylene disphosphonate and 99mTc-pentavalent DMSA compared with 99mTc-sestamibi for palpable breast lesions J Nucl Med. (2002) Jul; 43(7):882-8
A Trypanosoma cruzi small surface mucin-like molecule provides the first immunological evidence that Chagas´disease is due to a single parasite lineage J Exp Med. 2002 Feb 18;195(4):401-13.
Estudio intergeneracional de la mutacion que causa la distrofia miotonica de tipo 1 en Costa Rica Rev Neurol, 2002 (35)
Diagnostico directo de la mutacion que cause el syndrome de cromosoma X fragil: Experiencia en Costa Rica Acta Medica Costarricense, 2002, 44(1):27-33.
Phenotypic and sarcoglycan expressions in Tunisian LGMD 2C patients sharing the same del521-T mutation Neurology, 2002
A novel form of limb-girdle muscular dystrophy and mental retardation with reduced -dystroglycan Brain, 2002
Hepatitis C virus phylogeny: a useful clinical tool Acta virologica 46: 179 – 182, 2002.
Analysis of genetic heterogeneity of hepatitis C viruses in Central America reveals a novel genetic lineage Archives of Virology 147: 2239-2246, 2002.
The core-directed immune response in hepatitis C virus infection reveals a discontinuous epitope presented by the core N-terminal region Virus Reviews & Research 7, 2002.
Detection of mutations in the Plasmodium falciparum dihydrofolate reductase (dhfr) gene by dot-blot hybridisation Am J Trop Med Hyg. 2002 Jul;67(1):24-7.
Reseau d’Etude de la Reistance (RER) pour perenniser la surveillance de la sensibilite de Plasmodium falciparum aux antipaludiques a Madagascar Arch Inst Pasteur de Madagascar 2002; 68(1&2); 73-78.
Reseau d’Etude de la Reistance (RER) pour perenniser la surveillance de la sensibilite de Plasmodium falciparum aux antipaludiques a Madagascar Arch Inst Pasteur de Madagascar 2002; 68(1&2); 73-78.
Molecular analysis of clinical isolates of Mycobacterium tuberculosis collected from patients with persistent disease in the Khartoum region of Sudan J Infection, 00:1-8, 2002.
Novel IS6110 insertion sites in the direct repeat locus of Mycobacterium tuberculosis clinical strains from the St.Petersburg area of Russia, and evolutionary and epidemiological considerations J Clin Microbiol, 40(4):1504-1507, 2002.
Prediction of Drug Resistance in M.tuberculosis: Molecular mechanisms, tools and applications IUBMB Life 2002; 53: 231-7.
PCR diagnosis of tuberculosis in paucibacillary sputum samples in Ghana Ghana Medical Journal, 2002
Molecular detection of early appearance of drug resistance during Mycobacterium tuberculosis infection Clinical Chemistry and Laboratory Medicine 40 (9):876-881, 2002.
Predominance of a novel Mycobacterium Tuberculosis genotype in the Delhi region of India Tuberculosis (Edinb) 82(2-3):105-112, 2002.
Critical comparison of molecular genotyping methods for detection of drug resistant Plasmodium Falciparum Transactions of the Royal Society of Tropical Medicine and Hygiene 2002.96, 568-572.
The Frequency of pre-core Gene Mutations in Chronic Hepatitis B Infection: A Study of Malaysian Subjects Southeast Asian J Trop Med Public Health. 2002, 33(1); 102-109.
Human Papilloma Virus European Journal of Immunogenetics. 2002, (29): 417-421.
High prevalence of KatG Ser315Thr substitution among isoniazid-resistant Mycobacterium tuberculosis clinical isolates from northwestern Russia, 1996-2001 Antimicrob. Agents Chemother. 2002.46(5):1417-1424.
Nosocomial Outbreak of Multidrug Resistant Tuberculosis Caused by Mycobacterium tuberculosis W-Beijing Family Strain in St. Petersburg, Russia Eur. J. Clin. Microbiol. Infect. Dis. 21(8):596-602, 2002.
Isoniazid-Induced Transient High-level Resistance in Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy 46(9):2804-10, 2002.
Characterization of Mycobacterium tuberculosis strains circulating in the North-West of Russia by spoligotyping. Problemy Tuberculeza (Russian Journal)
Isolation of multi-drug resistant tuberculosis strains in patients from private and public health care facilities in Nairobi, Kenya Int J Tuberculosis Lung Dis, 2002,
A Trypanosoma cruzi small surface mucin-like molecule provides the first immunological evidence that Chagas´disease is due to a single parasite lineage J Exp Med. 2002 Feb 18;195(4):401-13.
Trypanosoma cruzi: isolation of an immunodominant peptide of TESA (Trypomastigote Excreted-Secreted Antigens) by gene cloning Diagnostic Microbiology Infection Disease 42(2002): 187-92.
Expression and genome-wide distribution of the gene family encoding a 90 kDa surface glycoprotein of metacyclic trypomastigotes of Trypanosoma cruzi Molecular and Biochemical Parasitology, 125(1-2):201-206, 2002.
Impact of the Polymerase chain reaction in diagnosis and treatment evaluation of congenital Chagas' disease J. Clinical Microbiology, 2002
Parasite detection in heart tissues in end stage Chagas heart disease American Heart Journal, 2002.
Trypanosoma cruzi small surface mucin-like molecular provides the first immunological evidence that Chagas’ disease is due to a single parasite lineage J Exp Med. 2002 Feb 18;195(4):401-13.
The Lys-76-Thr mutation in PfCRT and Chloroquine resistance in Plasmodium falciparum isolates from Uganda Trans Royal Soc Trop Med Hyg, 96:91-95, 2002.
Monitoring the drug-sensitivity of Plasmodium falciparum in coastal towns in Madagascar by use of in vitro chemosensitivity and mutation detection tests Parasite, 2002, 9(3): 247-253.
Current absence of pyrimethamine-resistance of Plasmodium falciparum in Madagascar Transactions of the Royal Society of Tropical Medicine and Hygiene, 96(5):557-559, 2002.
Evaluation in vitro de la sensibilité de Plasmodium falciparum à la chloroquine dans la région de l'Océan Indien dans le contexte du Réseau d'Etude de la Résistance (RER) September 2002, Cahiers Santé
Clearance Of Drug-Resistant Parasites As A Model For Protective Immunity In Falciparum Malaria
Intensity of malaria transmission, antimalarial-drug use and resistance in Uganda: what is the relationship between these three factors? Trans R Soc Trop Med Hyg, May-Jun;96(3):310-7, 2002.
A multi-centre study in order to define further the molecular basis of ß-thalassemia in Thailand, Pakistan, Sri Lanka, Mauritius, Syria and India, and to develop a simple molecular diagnostic strategy by ARMS-PCR. Hemoglobin, 2001, 25 (4) 397-407
Chagas disease: recombinant T.cruzi antigens for serological diagnosis Trends in Parasitol, 17: 286-291, 2001.
Isolation and characterisation of genomic and cDNA clones coding for a serine-, alanine-, and proline-rich protein of Trypanosoma cruzi International Journal for Parasitology, Volume 31, Issue 3, Pages 259-264, March 2001
Application of a molecular marker for surveillance of Chloroquine-resistant falciparum malaria Lancet, 358:890-891, 2001.
A molecular marker for Chloroquine-resistant falciparum malaria New Engl J Med, 344:-257-263, 2001
Can pretreatment screening for dhps and dhfr point mutations in Plasmodium falciparum infections be used to predict sulfadoxine-pyrimethamine treatment failure? Trans R Soc Trop Med Hyg. 2001 May-Jun;95(3):315-9, 2001
Plasmodium falciparum in Kenya: High prevalence of drug-resistance-associated polymorphisms in hospital admissions with severe malaria in an epidemic area Annals of Tropical Medicine and Parasitolog: 95, No. 7, 661-669, 2001.
Co-trimoxazole compared with sulfadoxine -pyrimethamine in the treatment of uncomplicated malaria in Kenyan children Trans R Soc Trop Med Hyg. 2001 Nov-Dec;95(6):657-60.
Use of DNA-based diagnostic methods for human leishmaniasis in Minas Gerais, Brazil Acta Trop. Mar 30;78(3):261-7, 2001
Treatment of Trypanosoma cruzi-infected children with nifurtimox: a 3 year follow-up by PCR Antimicrob Chemoth Jr, 48:515-519, 2001
Identification of Trypanosoma cruzi genotypes circulating in Chilean Chagasic patients Experim Paras, 97:226-233, 2001
Parasite persistence in treated chagasic patients revealed by xenodiagnosis and polymerase chain reaction Mem Inst Oswaldo Cruz.; 96(6):823-6, Aug 2001
Diagnóstico molecular de la Distrofia Miotónica (DM) en Costa Rica Acta Médica Costarricense, Vol 43 (4), 2001
Linkage of a new locus for autosomal recessive axonal form of Charcot-Marie Tooth disease to chromosome 8w21.3. Neuromuscular Disorders 11:27-34, 2001.
Detection of Mutations in Mycobacterium tuberculosis by a Dot Blot Hybridization Strategy In: Mycobacterium tuberculosis Protocols. Publisher – Humana Press Inc. Vol. 54, Chapter 11, pp 155-164, 2001
Analysis for a limited number of gene codons can predict drug resistance of Mycobacterium tuberculosis in a high incidence community J. Clin. Microbiol. 39, 636-641, 2001
Sequence polymorphism in the rrs gene of M.tuberculosis is deeply rooted within an evolutionary clade and s not associated with streptomycin resistance J Clin Micobiol 2001 Nov;39(11):4184-6.
Arylamine N-acetyltransferase of Mycobacterium tuberculosis is a polymorphic enzyme and a site of isoniazid metabolism Mol Microbiol 2001 Oct;42(2):309-17.
Diversification of hepatitis C viruses in South America reveals a novel genetic lineage Archives of Virology 146:1623-1629, 2001.
Genetic variability of hepatitis A virus in South America reveals a heterogeneity and co-circulation during epidemic outbreaks J Gen Virol 2001; 82:2657-52.
Isolation of DNA from Mycobacterium tuberculosis In: Mycobacterium tuberculosis protocols Humana Press Inc. Vol. 54, Chapter 2, pp 19-30, 2001
Hepatitis C virus in a group of hematological and oncohematological patients Rev Med Chile, 129:18-22, 2001.
Treatment of Trypanosoma cruzi-infected children with nifurtimox: a 3 year follow-up by PCR. Antimicrob Chemoth Jr. 48:515-519, 2001
Identification of Trypanosoma cruzi genotypes circulating in Chilean Chagasic patients. 97:226-233, 2001.
Chagas disease: recombinant T.cruzi antigens for serological diagnosis. Trends in Parasitol, 17: 286-291, 2001.
Combating infection in developing countries. The IAEA contribution Vienna (Austria), IAEA Aug (2000) 32 p. IAEA-PI-A--71E
Genetic factors affecting clinical severity in beta thalassemia syndromes. Official Journal of the American Society of Pediatric Hematology/Oncology, Volume 22, Issue 6, Pages 573-580, November - December 2000
Hepatitis B virus core promoter genetic variability: The role of mutations in disease outcome VIRUS Reviews and Research, pp. 41-48, 2000.
Molecular characterization of Mycobacterium tuberculosis strains from North-west region of Russia Epi North. 2000 2:22-24.
Mapping of IS6110 flanking regions in clinical isolates of M.tuberculosis demonstrates genome plasticity Mol Microb, 37(6):1405-1415, 2000
Rapid detection of alpha thalassaemia deletions and alpha globin gene triplication by multiplex polymerase chain reaction Br J Haematol 2000;108: 295-9
The genome sequence of the plant pathogen Xylella fastidiosa Nature, 406:151-157, 2000.
A new molecular biology and immunological laboratory in the Hospital Regional, Valdivia, Chile Rev Med Chile; 18:683-684, 2000.
High circulation of hepatitis B virus (HBV) precore mutants in Tunisia, North Africa Epidemiology & Infection . 125: 169-174, 2000.
Evaluation and Validation Of Electret Radiorespirometry: A Newly Developed Technique For Rapid Detection Of Microorganisms Journal of Medical Physics, 25(1), 41-45, 2000.
Frasch Trypanosoma cruzi surface mucins with exposed variant epitopes J Bio Chem, 275(36):27571-80, 2000
Immunoblot analysis of trypomastigote excreted-secreted antigens as a tool for the caharacterization of T.cruzi strains and isolates J. Parasit, 86(4):862-67, 2000
Early diagnosis of recurrence of T.cruzi infection by polymerase chain reaction after heart transplantation of a chronic Chagas’ heart disease patient The Journal of Hear and Lung Transplantation, 19(11):1114-1117, 2000
Evaluación de Antígenos Recombinantes para el Diagnóstico de la Enfermedad de Chagas Revista BIOFARBO Vol. VIII-Diciembre, 51-56, 2000
Indice de Infección por Trypanosoma cruzi en Habitantes del Cantón de Coripata de la Provincia Nor Yungas del Departamento de La Paz, Bolivia Revista BIOFARBO Vol VIII-Diciembre, 77 – 80, 2000
Linkage to chromosome 13q11-12 of an autosomal recessive cerebellar ataxia in a Tunisian family Neurology, Volume 54, Issue 7, Pages 1408-1414, April 11, 2000
A new locus for autosomal recessive limb-girdle muscular dystrophy in a large consanguienous Tunisian family maps to chromosome 19q13.3. Neuromuscular Disorders, 10:240-46
Rapid selection of P. falciparum DHFR mutants by pyrimethamine prophylaxis J Infect Dis 2000; 182(3): 993-6
A cross section of autosomal recessive limb-girdle muscular dystrophies in 38 families J Med Genet, 37: 361-367
Genetic Counseling for childless women at risk for Duchenne muscular dystrophy. Am.J.Med.Genet.86: 447-453, 1999
Further evidences for the organization of the four sarcoglycans proteins within the dystrophin-glycoprotein complex European Journal of Human Genetics 7: (2) 251-254, 1999
Adecuacion de una prueba radiometrica para la deteccion de resistencia multiple de Plasmodium falciparum a medicamentos BIOMEDICA 19(1): 25-34, 1999
Comparacion de tecnicas in vitro para detectar resistencia de Plasmodium falciparum a medicamentos BIOMEDICA 19(2):103-114, 1999
Expresion del gen asociado con la resistencia multiple a medicamentos (pfmdr1) en cepas colombianas de Plasmodium falciparum BIOMEDICA 19(3):198-206, 1999
Clinical and molecular analysis of spinal muscular atrophy in Brazilian patients Genetics and Molecular Biology 22: 487-492
Aspectos geneticos y moleculares de la distrofia miotonica Neuroeje, 13:82-89, 1999
Evidence of increasing diversification of hepatitis C viruses Journal of General Virology 80, 1377-1382, 1999
Electret Radiorespirometry (ERR): A Novel Method For Rapid Detection Of Microorganisms Journal of Medical Physics, India, 24(4),186-189, 1999.
Detection of mutations in drug resistance genes of Mycobacterium tuberculosis by a dot-blot hybridisation strategy Tuber Lung Dis, 79(6):343-348, 1999
The seven autosomal recessive limb-girdle muscular dystrophies (LGMD): from lgmd2a to lgmd2g Am. J. Med. Genet 82:392-398
Sarcoglycanopathies are responsible for 68% of severe autosomal recessive limb-girdle muscular dystrophy in the Brazilian population J.Neurol.Sciences 164: 44-49
Trypanosoma cruzi and human ubiquitin are immulogically distinct proteins despite only three amino acid difference in their primary sequence FEMS Immunology and Medical Microbiology 24 123-130, 1999
Myocardial parasite Persistence in Chronic Chagasic Patients Am. J. Trop. Med. Hyg. 60:726-732, 1999
Heterologous Expression of a Trypanosoma cruzi Surface Glycoprotein (gp82) in Mammalian Cells Indicates the Existence of Different Signal Sequence Requirements and Processing, J. Eukaryot Microbiol, 46(6):557-565, 1999
Serological diagnosis of Chagas disease with purified and defined T.cruzi antigens Mem Inst Oswaldo Cruz, Vol. 94, Suppl. I:285-88, 1999
Evaluation of recombinant antigens for Chagas’ disease serodiagnosis in South and Central America Journal of Clinical Microbiology, Volume 37, Issue 5, Pages 1554-1560, May 1999
Identification of three rare beta-thalassemia mutations in the Pakistani population Hemoglobin, August 1999
Early detection of typhoid by polymerase chain reaction Ann. Saudi Med. 19(4) 337-340, 1999.
Mutaciones inestables: causa de algunas enfermedades neurologicas hereditarias Acta Medica Costarricense, 41:7-15, 1999
The role of the IAEA in nuclear medicine European Journal of Nuclear Medicine, Feb (1999) v.26(2) p. 73-75
A distance-assisted training program for nuclear medicine technologists J Nucl Med Technol. (1999) Dec; 27(4):318-20
32-Phosphorus for bone pain palliation due to bony metastases, its safety and efficacy in patients with advanced cancer IAEA, Vienna (Austria) International seminar on therapeutic applications of radiopharmaceuticals. Programme. Book of extended synopses Dec (1998) 194 p.p. 137-139. IAEA-SR--209/50; IAEA-SR--209
In vitro radionuclide techniques in medical diagnosis IAEA-TECDOC-1001, 1998
Sweat electrolyte and cystic fibrosis mutations allows early diagnosis in Brazilian children with clinical signs compatible with cystic fibrosis American Journal of Medical Genetics, Volume 76, Issue 4, Pages 288-290, April 1, 1998
Different behaviour in the paternally versus the maternally inherited mutated allele in Brazilian Machado-Joseph (MJD1) families American Journal of Medical Genetics, Volume 77, Issue 3, Pages 246-248, May 18, 1998
Analysis of the 5-HTT polymorphism in the serotonin transporter gene regulatory region in Brazilian patients affected by bipolar disorder and schizophrenia American Journal of Medical Genetics, Volume 81, Issue 3, May 8, Pages 225-227, 1998
HCV serotypes and HCV-RNA quantitation Kor J Clin Pathol 18(2):259-264, 1998.
Métodos de diagnóstico directo (Chapter 64), Parasitología Médica Ed. A. Atías Edit Mediterráneo (book chapter) 1998.
Métodos de diagnóstico indirecta (Chapter 65). Parasitología Médica Ed. A. Atías Edit Mediterráneo, (book chapter) 1998.
Editores Tecnologías aplicadas al diagnóstico de enfermedades parasitarias Faculty of Medicine. University of Chile. (book chapter)1998.
A simple and rapid molecular typing of M.tuberculosis by polymerase chain reaction J. Microbiol., 36:124-129, 1998.
Diagnosis of pulmonary tuberculosis by polymerase chain reaction for MPB64 gene: an evaluation in a blind study Indian J Chest Dis Allied Sci, 40:5-16, 1998
Synthetic peptides of Trypanosoma cruzi antigens in the diagnosis of congenital Chagas disease Res Rev Parasitol 1998; 58: 43-47
Prevalence of fragile X (A) syndrome in mentally retarded children at a genetics referral centre in Delhi, India Indian J Med Res, Jul; 108:12-6, 1998
Electrophysiological and nerve biopsy comparative study in Friedreich’s ataxia and Friedreich ataxia phenotype with vitamin E deficiency Neuromuscular Disorders, Volume 8, Issue 6, Pages 416-425, August 1998
Paternal inheritance or different mutations in maternally related patients occur in about 3% of Duchenne familial cases Am J Med Genet 78:361-365, 1998
The Faxioscapulohumeral muscular dystrophy (FSHD1) gene affects males more severaly and more frequently than females Am J Med Genet 77:155-161
Detection of Leishmania DNA by polymerase chain reaction in scars of treated human cases J. Inf. Dis. 178(3): 911-914, 1998
Evaluation of PCR for Diagnosis of Leishmaniasis in Bolivian Patients Memorias del Instituto Oswaldo Cruz, 93(11),BI-115, 139, 1998
Prenatal diagnosis of beta-thalassemia: experience in a developing country. Prenat Diagn. 1998. Jan; 18(1):1-7
Characterization of Beta-Thalassemia in Pakistan Hemoglobin, 22(4), 335-345, 1998
Chagas’ Disease and HIV Co-infection: Genotypic Characterization of the Trypanosoma cruzi Strain Mem Inst Oswaldo Cruz, Rio de Janeiro, Vol. 93(2: 165-169, Mar./Apr. 1998
Development of molecular probes for diagnosis of Chagas disease using recombinant DNA technology serodiagnosis with recombinant antigents A Folha Medica, 16(1):27-31, 1998
Mapping of B cell epitopes in an immunodominant antigen of Trypanosoma cruzi using fusions to the Escherichia coli LamB protein FEMS Microbiology Letters, 164:125-131, 1998
Detection of Trypanosoma cruzi in vector and host by polymerase chain reaction amplification of nuclear DNA Memorias del Instituto Oswaldo Cruz, 93(11),BI-116, 139-140, 1998
User of trans-sialidase inhibition assay in a population serologically negative for Trypanosoma cruzi but at a high risk of infection Clin Diag Lab Immunol, 5:254-255, 1998
Isolation and characterization of Trypanosoma cruzi from a Brazilian HIV positive patient Mem. Inst. Oswaldo Cruz 93: 165-169, 1998
Parasite genotypically related to a monoxenous trypanosomatid of dog's flea causing opportunistic infection in an HIV positive patient Mem. Inst. Oswaldo Cruz 93: 531-7
Familial autosomal recessive inclusion body myositis with asymptomatic leukoencephalopathy In “Inclusion body myositis and myopathies”, Askanas, Serratrice & Engel, eds, Cambridge University Press, 211-220, 1997
The seventh form of autosomal recessive limb-girdle muscular dystrophy (LGMD2G) is mapped at 17q11-12 American Journal of Medical Genetics, 61, p. 151-159
Les ß-thalassemies Au Maroc: Etude Clinique Et Moleculaire Archive de Pasteur, 1997, 11, 22-30
The spectrum of beta-thalassemia mutations in the Lebanon Hum Hered, 47(5):241-9, 1997
Incidence of endocrine complications and clinical disease severity related to gentoype analysis and iron overload in patients with beta-thalassemia Eur J Haematol, 59(2):76-81, 1997
A simple Trypanosoma cruzi enzyme linked immunoassay for control of human infection in nonendemic areas FEMS, Immunol. Med. Microbiol. 18, 31-37, 1997
Immunization with recombinant Trypanosoma cruzi ribosomal P protein induces changes in the electrocardiogram of immunized mice FEMS Immunol. Med. Microbiol. 18,75-85, 1997
More on Chagas Disease Cardiomyopathy Parasitol. Today, 13 (9) 362-363, 1997
Antibodies to ribosomal P proteins of Trypanosoma cruzi in Chagas disease possess functional autoreactivity with heart tissue and differ from anti-P autoantibodies in Lupus Proc. Natl. Acad. Sci. 94, 10301-10306, 1997
Characterization of a reiterated family of interspersed DNA elements in the genome of Trypanosoma cruzi Parasitolology 115, 563-570, 1997
Segregation distortion of the CTG repeats at the myotonic dystrophy (DM) locus: new data from Brazilian DM families, 1997 Journal of Medical Genetics, 34, pg. 790-791.
Novel point mutations in the dystrophin gene Human Mutation, 10, p. 217-222
Effect of Itraconazole on lytic antibodies levels in chronic Chagas disease Parasite 4, 259-262, 1997
Molecular karyotype and schizodeme analyses of Trypanosoma cruzi stocks from Chilean triatomines Parasitology 115, 41-46, 1997
Homozyogosity mapping of giant axonal neuropathy gene to chromosome 16q24.1 Neurogenetics Vol. 1, No., Oxford University Press, 1997
Friedreich’s ataxia with isolated vitamin E deficiency: a neuropathological study of a Tunisian patient Acta Neuropathologica, Volume 93, Issue 6, June 1997, Pages 633-637.
Cholinergic autoantibodies in sinus node dysfunction Lancet 350, 262- 263, 1997.
Annual report on external quality assessment in immunoserology in Korea for 1996. J Clin Pathol & Quality Control 19(1):49-87, 1997.
An external standard method for quantification of human cytomegalovirus by PCR Journal of Radioanalitical Nuclear Chemistry 221(1997)143-147.
Review on quantitative PCR assay Journal of Radioanalitical Nuclear Chemistry 221(1997)137-142.
Hepatitis C Virus Genotypes in Peninsular Malaysia Asia Pacific Journal of Molecular Biology and Biotechnology, Volume 5, No. 2, August 1997.
HCV genotypes determined by polymerase chain reaction with type-specific primers in Korean HCV-infected patients and HCV-positive blood donors Focus on Genetic Science 5:68-7, 1997.
Genotypage Des Souches Marocaines Responsable De L'hépatite C Archive de l'institut Pasteur, 1997, 10, 43 – 47.
Comparison of molecularbiologic methods for detecting HBV-DNA in the sera which showed both Hepatitis B surface antigen and antibody positivity Kor J Clin Pathol, 17(6):1124-1136, 1997.
Evaluation of the Genedia HCV ELISA 3.0 and Genedia HCV PHA for anti-HCV antibody detection J Clin Pathol & Quality Control, 19(2): 383-392, 1997.
Combined interpretation of pretransplant anti-HCV Ab by 3rd generation ELISA and HCV-RNA by PCR for the prediction of post-transplant liver dysfunction J Kor Soc Transpl 11(1):73-80, 1997.
Estudio epidemiológico y patológico en donantes positivos a enfermedad de Chagas en el banco de sangre del Hospital San Juan de Dios Rev. Med. Chile. 1997, 125:905-910
Expression of a Trypanosoma cruzi surface glycoprotein (gp82) by mammalian cells indicate the existence of different signal sequence requirements and processing Memorias do Instituto Oswaldo Cruz, vol. 92, Suppl. I, Nov. 1997, page 162.
Isolation and characterization of Tryapanosoma cruzi recombinant antigens with antibodies from Chilean patients Memorias do Instituto Oswaldo Cruz, vol. 92, Suppl. I. Nov. 1997, page 205.
The Trypanosoma cruzi genome initiative Parasitol. Today 13, 16-22, 1997
Long-lasting antibodies detected by a trans-sialidase inhibition assay in parasite free/serologically cured chagasic patients J Infect Dis, 175:1272-1275, 1997
Etude De L'informativité Des Rflp Dans L'hémophilie A Au Maroc Archive de Pasteur, 1997, 11, 46-53
Case study on the results of image interpretation An IAEA (CRP) group study (1996) 311 p.p. 119-299. INIS-XA--293
Nuclear applications for health Canadian Nuclear Society Bulletin, Aug (1995), v.16(3) p. 16-19
Health and the environment: Examining some interconnections IAEA Bulletin, 36:4 (1994) 10-17
Radionuclides in molecular technology for diagnosis of communicable diseases IAEA-TECDOC-748, 1994
Nuclear medicine activities at the IAEA European Journal of Nuclear Medicine, Nov (1993), v.20(11) p. 1047-1050
Treating tumours with radionuclides Vienna (Austria). IAEA Yearbook (1993). Sep 1993. 307 p.p. B21-B37. STI/PUB--935
Radioimmunoassay in developing countries: General principles IAEA, Vienna (Austria). Nuclear Medicine Section Handbook of nuclear medicine practice in developing countries (1992) 728 p.p. 191-260
DNA probes IAEA, Vienna (Austria). Nuclear Medicine Section Handbook of nuclear medicine practice in developing countries (1992) 728 p.p. 273-291
Nuclear cardiology IAEA, Vienna (Austria). Nuclear Medicine Section Handbook of nuclear medicine practice in developing countries (1992) 728 p.p. 373-442
In vitro thyroid testing in populations with low thyroxine binding globulin capacity IAEA, Vienna (Austria). Nuclear Medicine Section Handbook of nuclear medicine practice in developing countries (1992) 728 p.p. 261-272
Quality control of nuclear medicine instruments IAEA-TECDOC-602, 1991, also in Spanish, IAEA-TECDOC-602S
Diagnosing diseases of the lung Applications of nuclear techniques and research 1990. Part B of the IAEA Yearbook 1990. Vienna (Austria). IAEA (1990). 81 p.p. 39-50
Atlas of Liver Imaging IAEA-TECDOC-501, 1989
Radiation Technology for Immobilization of Bioactive Materials IAEA-TECDOC-486, 1989
Radioimmunoassay for human health in developing countries IAEA Bulletin, 29:4 (1987) 41-44
Nuclear and Related Techniques in Parasitology IAEA-TECDOC-371, 1986
IAEA activities in nuclear medicine and related medical applications of nuclear techniques Proceedings of an international symposium on nuclear medicine and related medical applications of nuclear techniques in developing countries held in Vienna, 26-30 Aug 1985. Vienna (Austria). IAEA (1986). 645 p.p. 531-543. IAEA-SM--283/113
IAEA programme on maintenance of nuclear instruments Proceedings of an international symposium on nuclear medicine and related medical applications of nuclear techniques in developing countries held in Vienna, 26-30 Aug 1985. Vienna (Austria). IAEA (1986). 645 p.p. 531-543. IAEA-SM--283/109
Quality control of nuclear medicine instruments IAEA-TECDOC-317, 1984
The optimization of nuclear medicine procedures for the diagnosis and management of thyroid disorders in developing countries. Nuclear Medicine Communications UK. May (1984). v.5(5) p. 339-351
Use and maintenance of nuclear medicine instruments in South East Asia IAEA-TECDOC-281, 1983
Radioimmunoassay (RIA) data processing on programmable calculators: an IAEA project Proceedings of an international symposium on radioimmunoassay and related procedures in medicine organized by the IAEA and held in Vienna, Austria, 21-25 Jun 1982. Vienna. IAEA (1982). 825 p.p. 411-421. IAEA-SM--259/88
Characteristics of commercially available well scintillation counting systems and liquid scintillation counting systems Proceedings of an international symposium held by the IAEA in co-operation with the WHO in Berlin (West), 31 Oct - 4 Nov 1977. Vienna. IAEA (1978). v.1 p. 517-538
Bone irradiation in thorotrast cases: results of measurements at IAEA Health Physics USA. Jul (1978). v.35(1) p. 103-112
Well scintillation counter with automatic sample changing and data processing: an inexpensive instrument incorporating consumer products International symposium on radioimmunoassay and related procedures in medicine. Berlin, Germany, F.R. 31 Oct - 4 Nov (1977). 17 p. AED-Conf--77-461-061, IAEA-SM--220/121
Characteristics of commercially available well scintillation counting systems International symposium on radioimmunoassay and related procedures in medicine. Berlin, Germany, F.R. 31 Oct - 4 Nov (1977). 17 p. AED-Conf--77-461-062, IAEA-SM--220/122
Maintenance of nuclear medicine instruments in developing countries IAEA-TECDOC-184, 1976
Thorium series radionuclides in compact bone of thorotrast cases - results of measurements at IAEA Proceedings of the 3. international meeting on toxicity of thorotrast held at the Finsen Institute, Copenhagen April 25-27 1973. Sponsored by the DAEC, the National Health Service of Denmark and WHO. Jun (1973) p.81-94. RISO--294
Half life of sup 1 sup 3 sup 2 Cs Health Physics USA. Jul (1973). v.25(1) p. 82-83